Pharmaceutical Solutions I: Simple, Saturated, Syrups: Labs
Laboratory Procedures
1. Preparation of a simple solution. Prepare, label, and dispense the following prescription.
Jacquelyn Hyde, MD Rx# 51601
123 Upendown Rd.
Nowhere, NC 27000
Phone: 555-1234 DEA# AH0079411
Name: Pat Annsir Date: Today
Address: 123 Della Street Phone: 555-5678
Rx
Sodium citrate dihydrate 1N
Citric acid anhydrous 1N
Aqua. dist. q.s. ad 3 fl. oz.
Sig: i tsp diluted in juice or water p.c. and h.s.
Refills: 1
Product selection permitted Dispense as written
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Determine the pH of the final solution.
View a video demonstration on how to use a pH meter
2. Preparation of a saturated solution. Using the formula for SSKI provided in Remington’s, prepare, label, and dispense the following prescription. Calibrate a dropper to deliver the prescribed amount of medication; label dose in drops.
Jacquelyn Hyde, MD Rx# 51602
123 Upendown Rd.
Nowhere, NC 27000
Phone: 555-1234 DEA# AH0079411
Name: Luce Morals Date: Today
Address: 123 Jackla Lane Phone: 555-5678
Rx
SSKI 20 ml
Sig: 0.25 ml q.i.d.
Refills: 2
Product selection permitted Dispense as written
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3. Preparation of a simple solution from commercial tablets. Compound the following prescription, using commercially prepared tablets, each containing 0.2 mg Clonidine HCl.
Mel Batost, MD Rx# 51603
123 Upendown Rd.
Nowhere, NC 27000
Phone: 555-1234 DEA# AH0079411
Name: Lee Mealone (Age 2 mo.) Date: Today
Address: 321 Memory Lane Phone: 555-1234
Rx
Clonidine HCL 1.5 mg %
Aqua. Dist. q.s. ad. 50 ml
Sig: 0.03 mg p.o. q6h
no refill
Product selection permitted Dispense as written
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4. Preparation of Simple Syrup. Using the formulation provided in Remington’s, prepare 100 ml of simple syrup by the “solution with heat” method. Label Rx 51604, and put only “Simple Syrup,” your name, and the date of preparation.
5. Preservation of guaifenesin syrup. Using alcohol as a preservative, prepare a medicinal syrup of guaifenesin. Assume that the volume occupied by the guaifenesin is negligible.
I. Ben Hadd, MD Rx# 51605
123 Upendown Rd.
Nowhere, NC 27000
Phone: 555-1234 DEA# AH0079411
Name: Cindy Rella Date: Today
Address: 123 Jackla Lane Phone: 555-5678
Rx
Guaifenesin 2%
Alcohol, USP q.s.
Flavoring agent of choice q.s.
Purified water q.s. ad 100 ml
M.ft. syrup
Sig: 1-2 tsp. q4-6 h, p.r.n.
Refills: 2
Product selection permitted Dispense as written
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Laboratory Data
Calculations and compounding procedures should be ready for TAs to check at the beginning of lab!
1. Prescription #51601: Preparation of a simple solution
Sodium Citrate dihydrate _______________________ g
Citric Acid (anhydrous) ________________________ g
Distilled Water q.s. ___________________________ ml
Calculations:
Compounding Procedure:
Therapeutic use:_________________________
pH of final product:___________
Inspection of final product:________
2. Prescription #51602: Preparation of a saturated solution
KI ______________ g
Distilled water, q.s. _____________ml
Calibrated dropper: 2 ml =______ drops; drops per 0.25 ml dose =______ drops
Calculations:
Compounding Procedure:
Therapeutic use:__________________
Inspection of final product:_______
3. Prescription #51603: Preparation of simple solution from commercial tablets
Clonidine HCl 0.2 mg/tablet __________ tablets
Distilled water q.s ___________ ml
Calculations:
Compounding Procedure:
Therapeutic use:_______________
Inspection of final product:________
4. Preparation of Simple Syrup: (Label #51604)
Sucrose_________ g
Distilled water___________ ml
Compounding Procedure:
Inspection of final product:________________
5. Prescription #51605: Preparation of guaifenesin syrup
Guaifenesin __________ g
Alcohol USP __________ ml
Flavoring agent_______ ml
Therapeutic use: __________________
Compounding Procedure:
Inspection of final product:______________