The Pharmaceutics and Compounding Laboratory
Ointments: Preparation and
Evaluation of Drug Release

Sealing an Ointment Tube

Video
View a video demonstration on how to
seal an ointment tube

Wrapping Materials Prepare the ointment and place inside the tube. Leave about 1" empty at the bottom of the tube. Flatten about 1" of the bottom of the tube with a spatula.
In the next several steps, you will make 3 folds in the ointment tube.
Cutting foil into sections
First Fold:
Make a crease about 1/8" from the bottom of the tube with the edge of the spatula. Fold the tube completely over the spatula.
Place the suppository in the center

Second Fold:
With the first fold facing up, make a crease about 1/4" from the bottom of the tube.

Fold bottom up Fold the tube completely over the spatula...
Fold top down ...a side view.
Fold left side in

Third Fold:
Turn the tube over (i.e., no folds showing), and make a crease about 1/8" from the bottom of the tube. This time, do not fold the tube completely over the spatula, but only until the tube is perpendicular to the surface.

Roll suppository to wrap in foil A "T" will appear in the bottom of the tube...
Roll suppository to wrap in foil ...a side view.
Roll suppository to wrap in foil Place the metal clip on the "T"...
Roll suppository to wrap in foil ... and crimp with pliers or a tube crimper.
Roll suppository to wrap in foil Place the tube in the ointment tube box, and affix appropriate label(s).