The Pharmaceutics and Compounding Laboratory
Pharmaceutical Solutions III:
Ophthalmic Solutions

Learning Objectives

Upon completion of this exercise, you should be able to:

  • Define buffers, buffer capacity, isotonicity, iso-osmoticity, osmotic pressure, hypertonicity, hypotonicity.
  • Describe the use buffers in pharmaceutical solutions.
  • Identify the range of solution pH considered safe for ophthalmic solutions.
  • Formulate and analyze a buffer solution of desired pH and buffer capacity.
  • Explain the importance of isotonicity in ophthalmic solutions.
  • Explain the importance of sterility in ophthalmic solutions.
  • Explain the role of preservatives in pharmaceutical solutions.
  • Formulate and prepare pharmaceutically and physiologically acceptable ophthalmic solutions.